Targeting the GFI1/1B—CoREST Complex in Acute Myeloid Leukemia

One of the hallmarks of acute myeloid leukemia (AML) is a block in cellular differentiation. Recent studies have shown that small molecules targeting Lysine Specific Demethylase 1A (KDM1A) may force the malignant cells to terminally differentiate. KDM1A is a core component of the chromatin binding C...

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Detalles Bibliográficos
Autores principales: van Bergen, Maaike G. J. M., van der Reijden, Bert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794713/
https://www.ncbi.nlm.nih.gov/pubmed/31649884
http://dx.doi.org/10.3389/fonc.2019.01027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794713/
https://www.ncbi.nlm.nih.gov/pubmed/31649884
http://dx.doi.org/10.3389/fonc.2019.01027

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