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Histone methyltransferase SUV39H2 regulates cell growth and chemosensitivity in glioma via regulation of hedgehog signaling

BACKGROUND: Malignant glioma is one of the essentially incurable tumors with chemoresistance and tumor recurrence. As a histone methyltransferase, SUV39H2 can trimethylate H3K9. SUV39H2 is highly expressed in many types of human tumors, while the function of SUV39H2 in the development and progressio...

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Detalles Bibliográficos
Autores principales: Wang, Ran, Cheng, Lilin, Yang, Xi, Chen, Xin, Miao, Yifeng, Qiu, Yongming, Zhou, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794832/
https://www.ncbi.nlm.nih.gov/pubmed/31636512
http://dx.doi.org/10.1186/s12935-019-0982-z