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Histone methyltransferase SUV39H2 regulates cell growth and chemosensitivity in glioma via regulation of hedgehog signaling

BACKGROUND: Malignant glioma is one of the essentially incurable tumors with chemoresistance and tumor recurrence. As a histone methyltransferase, SUV39H2 can trimethylate H3K9. SUV39H2 is highly expressed in many types of human tumors, while the function of SUV39H2 in the development and progressio...

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Detalles Bibliográficos
Autores principales:	Wang, Ran, Cheng, Lilin, Yang, Xi, Chen, Xin, Miao, Yifeng, Qiu, Yongming, Zhou, Zhiyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794832/ https://www.ncbi.nlm.nih.gov/pubmed/31636512 http://dx.doi.org/10.1186/s12935-019-0982-z

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