Ionizing radiation increases the endothelial permeability and the transendothelial migration of tumor cells through ADAM10-activation and subsequent degradation of VE-cadherin

BACKGROUND: We analyzed the changes in permeability of endothelial cell layers after photon irradiation, with a focus on the metalloproteases ADAM10 and ADAM17, and on VE-cadherin, components crucial for the integrity of endothelial intercellular junctions, and their roles in the transmigration of c...

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Detalles Bibliográficos
Autores principales: Kouam, Pascaline Nguemgo, Rezniczek, Günther A., Adamietz, Irenäus A., Bühler, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794838/
https://www.ncbi.nlm.nih.gov/pubmed/31619190
http://dx.doi.org/10.1186/s12885-019-6219-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794838/
https://www.ncbi.nlm.nih.gov/pubmed/31619190
http://dx.doi.org/10.1186/s12885-019-6219-7

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