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Puerarin inhibits the osteoclastogenesis by inhibiting RANKL-dependent and –independent autophagic responses

BACKGROUND: Puerarin exerts therapeutic effect on osteoporosis due to its inhibitory effect on the formation of osteoclasts. Puerarin is also widely established as an autophagy inhibitor. The study aimed to investigate the significance of autophagy in Puerarin-treated osteoclast formation. METHODS:...

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Detalles Bibliográficos
Autores principales: Zhang, Guoyou, Wang, Yu, Tang, Guoke, Ma, Yuanzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794871/
https://www.ncbi.nlm.nih.gov/pubmed/31615565
http://dx.doi.org/10.1186/s12906-019-2691-5