Enhanced Cellular Uptake Of Phenamil Through Inclusion Complex With Histidine Functionalized β-Cyclodextrin As Penetrative Osteoinductive Agent

BACKGROUND: Phenamil (PH) is a small molecule that induces bone formation through upregulation of the TRB3 gene in the bone-regeneration process. β-Cyclodextrins (βCDs) with hydrophilic surfaces and a relatively hydrophobic cavity can form inclusion complexes with primarily hydrophobic small molecul...

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Detalles Bibliográficos
Autores principales: Jahed, Vahid, Vasheghani-Farahani, Ebrahim, Bagheri, Fatemeh, Zarrabi, Ali, Fink, Trine, Lambertsen Larsen, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794949/
https://www.ncbi.nlm.nih.gov/pubmed/31632029
http://dx.doi.org/10.2147/IJN.S221669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794949/
https://www.ncbi.nlm.nih.gov/pubmed/31632029
http://dx.doi.org/10.2147/IJN.S221669

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