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The −839(A/C) Polymorphism in the ECE1 Isoform b Promoter Associates With Osteoporosis and Fractures

CONTEXT: We previously found that variation in a quantitative trait locus, including the gene-encoding endothelin-converting enzyme 1 (Ece1), accounted for 40% of the variance in bone biomechanics and bone mineral density (BMD) in an intercross of recombinant congenic mouse strains. OBJECTIVE: We hy...

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Detalles Bibliográficos
Autores principales: Hansen, Karen E, Johnson, Michael G, Carter, Tonia C, Mayer, John, Keuler, Nicholas S, Blank, Robert D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795020/
https://www.ncbi.nlm.nih.gov/pubmed/31637345
http://dx.doi.org/10.1210/js.2019-00057