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Treatment of Ventilator-associated Pneumonia with High-dose Colistin Under Continuous Veno-venous Hemofiltration

BACKGROUND AND OBJECTIVES: High-dose colistin (COL) ensures adequate treatment of pneumonia caused by multidrug resistant gram-negative bacteria (MDR-GNB) but must be weighed against a higher risk of nephrotoxicity. Continuous veno-venous hemofiltration (CVVH) clears COL by filtering and membrane ad...

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Detalles Bibliográficos
Autores principales: Spapen, Herbert, van Laethem, Johan, Hites, Maya, Verdoodt, An, Diltoer, Marc, Honoré, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795054/
https://www.ncbi.nlm.nih.gov/pubmed/31637180
http://dx.doi.org/10.2478/jtim-2019-0022