SAR1B GTPase is necessary to protect intestinal cells from disorders of lipid homeostasis, oxidative stress, and inflammation

Genetic defects in SAR1B GTPase inhibit chylomicron (CM) trafficking to the Golgi and result in a huge intraenterocyte lipid accumulation with a failure to release CMs and liposoluble vitamins into the blood circulation. The central aim of this study is to test the hypothesis that SAR1B deletion (SA...

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Detalles Bibliográficos
Autores principales: Sané, Alain, Ahmarani, Lena, Delvin, Edgard, Auclair, Nikolas, Spahis, Schohraya, Levy, Emile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795079/
https://www.ncbi.nlm.nih.gov/pubmed/31409740
http://dx.doi.org/10.1194/jlr.RA119000119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795079/
https://www.ncbi.nlm.nih.gov/pubmed/31409740
http://dx.doi.org/10.1194/jlr.RA119000119

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