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Pearl-Necklace-Like Local Ordering Drives Polypeptide Collapse

[Image: see text] The collapse of the polypeptide backbone is an integral part of protein folding. Using polyglycine as a probe, we explore the nonequilibrium pathways of protein collapse in water. We find that the collapse depends on the competition between hydration effects and intrapeptide intera...

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Detalles Bibliográficos
Autores principales: Majumder, Suman, Hansmann, Ulrich H. E., Janke, Wolfhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795215/
https://www.ncbi.nlm.nih.gov/pubmed/31631912
http://dx.doi.org/10.1021/acs.macromol.9b00562