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miR-486 is modulated by stretch and increases ventricular growth

Perturbations in biomechanical stimuli during cardiac development contribute to congenital cardiac defects such as hypoplastic left heart syndrome (HLHS). This study sought to identify stretch-responsive pathways involved in cardiac development. miRNA-Seq identified miR-486 as being increased in car...

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Detalles Bibliográficos
Autores principales: Lange, Stephan, Banerjee, Indroneal, Carrion, Katrina, Serrano, Ricardo, Habich, Louisa, Kameny, Rebecca, Lengenfelder, Luisa, Dalton, Nancy, Meili, Rudolph, Börgeson, Emma, Peterson, Kirk, Ricci, Marco, Lincoln, Joy, Ghassemian, Majid, Fineman, Jeffery, del Álamo, Juan C., Nigam, Vishal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795397/
https://www.ncbi.nlm.nih.gov/pubmed/31513548
http://dx.doi.org/10.1172/jci.insight.125507