Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling

Type I interferons (IFNs) play a critical role in host defense against influenza virus infection, and the mechanism of influenza virus to evade type I IFNs responses remains to be fully understood. Here, we found that progranulin (PGRN) was significantly increased both in vitro and in vivo during in...

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Detalles Bibliográficos
Autores principales: Wei, Fanhua, Jiang, Zhimin, Sun, Honglei, Pu, Juan, Sun, Yipeng, Wang, Mingyang, Tong, Qi, Bi, Yuhai, Ma, Xiaojing, Gao, George Fu, Liu, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795447/
https://www.ncbi.nlm.nih.gov/pubmed/31585000
http://dx.doi.org/10.1371/journal.ppat.1008062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795447/
https://www.ncbi.nlm.nih.gov/pubmed/31585000
http://dx.doi.org/10.1371/journal.ppat.1008062

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