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Synthetic presentation of noncanonical Wnt5a motif promotes mechanosensing-dependent differentiation of stem cells and regeneration

Noncanonical Wnt signaling in stem cells is essential to numerous developmental events. However, no prior studies have capitalized on the osteoinductive potential of noncanonical Wnt ligands to functionalize biomaterials in enhancing the osteogenesis and associated skeleton formation. Here, we inves...

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Detalles Bibliográficos
Autores principales: Li, Rui, Lin, Sien, Zhu, Meiling, Deng, Yingrui, Chen, Xiaoyu, Wei, Kongchang, Xu, Jianbin, Li, Gang, Bian, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795506/
https://www.ncbi.nlm.nih.gov/pubmed/31663014
http://dx.doi.org/10.1126/sciadv.aaw3896