Targeting CCR5 trafficking to inhibit HIV-1 infection

Using a cell-based assay monitoring differential protein transport in the secretory pathway coupled to high-content screening, we have identified three molecules that specifically reduce the delivery of the major co-receptor for HIV-1, CCR5, to the plasma membrane. They have no effect on the closely...

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Detalles Bibliográficos
Autores principales: Boncompain, Gaelle, Herit, Floriane, Tessier, Sarah, Lescure, Aurianne, Del Nery, Elaine, Gestraud, Pierre, Staropoli, Isabelle, Fukata, Yuko, Fukata, Masaki, Brelot, Anne, Niedergang, Florence, Perez, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795511/
https://www.ncbi.nlm.nih.gov/pubmed/31663020
http://dx.doi.org/10.1126/sciadv.aax0821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795511/
https://www.ncbi.nlm.nih.gov/pubmed/31663020
http://dx.doi.org/10.1126/sciadv.aax0821

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