Controlled ploidy reduction of pluripotent 4n cells generates 2n cells during mouse embryo development

Cells with high ploidy content are common in mammalian extraembryonic and adult tissues. Cell-to-cell fusion generates polyploid cells during mammalian development and tissue regeneration. However, whether increased ploidy can be occasionally tolerated in embryonic lineages still remains largely unk...

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Detalles Bibliográficos
Autores principales: Frade, João, Nakagawa, Shoma, Cortes, Paola, di Vicino, Umberto, Romo, Neus, Lluis, Frederic, Cosma, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795515/
https://www.ncbi.nlm.nih.gov/pubmed/31663024
http://dx.doi.org/10.1126/sciadv.aax4199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795515/
https://www.ncbi.nlm.nih.gov/pubmed/31663024
http://dx.doi.org/10.1126/sciadv.aax4199

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