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Controlled ploidy reduction of pluripotent 4n cells generates 2n cells during mouse embryo development
Cells with high ploidy content are common in mammalian extraembryonic and adult tissues. Cell-to-cell fusion generates polyploid cells during mammalian development and tissue regeneration. However, whether increased ploidy can be occasionally tolerated in embryonic lineages still remains largely unk...
Autores principales: | Frade, João, Nakagawa, Shoma, Cortes, Paola, di Vicino, Umberto, Romo, Neus, Lluis, Frederic, Cosma, Maria Pia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795515/ https://www.ncbi.nlm.nih.gov/pubmed/31663024 http://dx.doi.org/10.1126/sciadv.aax4199 |
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