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Design, synthesis, and structural elucidation of novel NmeNANAS inhibitors for the treatment of meningococcal infection

Neisseria meningitidis is the primary cause of bacterial meningitis in many parts of the world, with considerable mortality rates among neonates and adults. In Saudi Arabia, serious outbreaks of N. meningitidis affecting several hundreds of pilgrims attending Hajj in Makkah were recorded in the 2000...

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Detalles Bibliográficos
Autores principales: Alwassil, Osama I., Chandrashekharappa, Sandeep, Nayak, Susanta K., Venugopala, Katharigatta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795526/
https://www.ncbi.nlm.nih.gov/pubmed/31618227
http://dx.doi.org/10.1371/journal.pone.0223413