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B cell receptor repertoire analysis in six immune-mediated diseases

B cells are important in the pathogenesis of many, and perhaps all, immune-mediated diseases (IMDs). Each B cell expresses a single B cell receptor (BCR)(1), with the diverse range of BCRs expressed by an individual’s total B cell population being termed the “BCR repertoire”. Our understanding of th...

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Detalles Bibliográficos
Autores principales: Bashford-Rogers, RJM, Bergamaschi, L, McKinney, EF, Pombal, DC, Mescia, F, Lee, JC, Thomas, DC, Flint, SM, Kellam, P, Jayne, DRW, Lyons, PA, Smith, KGC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795535/
https://www.ncbi.nlm.nih.gov/pubmed/31554970
http://dx.doi.org/10.1038/s41586-019-1595-3