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Fast and efficient copper-mediated (18)F-fluorination of arylstannanes, aryl boronic acids, and aryl boronic esters without azeotropic drying

BACKGROUND: Copper-mediated radiofluorination is a straightforward method to produce a variety of [(18)F]fluoroarenes and [(18)F]fluoroheteroarenes. To minimize the number of steps in the production of (18)F-labelled radiopharmaceuticals, we have developed a short and efficient azeotropic drying-fre...

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Detalles Bibliográficos
Autores principales: Lahdenpohja, Salla Orvokki, Rajala, Noora Annika, Rajander, Johan, Kirjavainen, Anna Kaarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795642/
https://www.ncbi.nlm.nih.gov/pubmed/31659523
http://dx.doi.org/10.1186/s41181-019-0079-y