Neuronal Cell-Intrinsic Defects in Mouse Models of Down Syndrome

Down Syndrome (DS) is the most common genetic disorder associated with intellectual disability (ID). Excitatory neurons of DS patients and mouse models show decreased size of dendritic field and reduction of spine density. Whether these defects are caused by cell autonomous alterations or by abnorma...

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Detalles Bibliográficos
Autores principales: Chiotto, Alessandra Maria Adelaide, Migliorero, Martina, Pallavicini, Gianmarco, Bianchi, Federico Tommaso, Gai, Marta, Di Cunto, Ferdinando, Berto, Gaia Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795679/
https://www.ncbi.nlm.nih.gov/pubmed/31649502
http://dx.doi.org/10.3389/fnins.2019.01081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795679/
https://www.ncbi.nlm.nih.gov/pubmed/31649502
http://dx.doi.org/10.3389/fnins.2019.01081

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