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Neuronal Cell-Intrinsic Defects in Mouse Models of Down Syndrome
Down Syndrome (DS) is the most common genetic disorder associated with intellectual disability (ID). Excitatory neurons of DS patients and mouse models show decreased size of dendritic field and reduction of spine density. Whether these defects are caused by cell autonomous alterations or by abnorma...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795679/ https://www.ncbi.nlm.nih.gov/pubmed/31649502 http://dx.doi.org/10.3389/fnins.2019.01081 |