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Auranofin Mediates Mitochondrial Dysregulation and Inflammatory Cell Death in Human Retinal Pigment Epithelial Cells: Implications of Retinal Neurodegenerative Diseases

PURPOSE: Photoreceptor degeneration occurs in various retinal diseases including age-related macular degeneration (AMD), Retinitis pigmentosa (RP), and diabetic retinopathy (DR). However, molecular mechanisms are not fully understood yet. The retinal pigment epithelium (RPE) forms the outer blood re...

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Detalles Bibliográficos
Autores principales: Yumnamcha, Thangal, Devi, Takhellembam Swornalata, Singh, Lalit Pukhrambam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795687/
https://www.ncbi.nlm.nih.gov/pubmed/31649499
http://dx.doi.org/10.3389/fnins.2019.01065