Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion

Extracellular phosphate regulates its own renal excretion by eliciting concentration-dependent secretion of parathyroid hormone (PTH). However, the phosphate-sensing mechanism remains unknown and requires elucidation for understanding the aetiology of secondary hyperparathyroidism in chronic kidney...

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Detalles Bibliográficos
Autores principales: Centeno, Patricia P., Herberger, Amanda, Mun, Hee-Chang, Tu, Chialing, Nemeth, Edward F., Chang, Wenhan, Conigrave, Arthur D., Ward, Donald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795806/
https://www.ncbi.nlm.nih.gov/pubmed/31619668
http://dx.doi.org/10.1038/s41467-019-12399-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795806/
https://www.ncbi.nlm.nih.gov/pubmed/31619668
http://dx.doi.org/10.1038/s41467-019-12399-9

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