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NPI-0052 and γ-radiation induce a synergistic apoptotic effect in medulloblastoma

Medulloblastoma (MB) is the most common malignant solid paediatric brain tumour. The standard treatment for MB is surgical resection of the tumour, radiation and chemotherapy. This therapy is associated with high morbidity and adverse side effects. Hence, more targeted and less toxic therapies are v...

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Detalles Bibliográficos
Autores principales: Frisira, Eleni, Rashid, Fatima, Varma, Swastina Nath, Badodi, Sara, Benjamin-Ombo, Valentine Ayodele, Michod, David, Niklison-Chirou, Maria Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795856/
https://www.ncbi.nlm.nih.gov/pubmed/31619667
http://dx.doi.org/10.1038/s41419-019-2026-y