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Magnetic resonance spectroscopy evidence for declining gliosis in MS patients treated with ocrelizumab versus interferon beta-1a

BACKGROUND: Magnetic resonance spectroscopy quantitatively monitors biomarkers of neuron-myelin coupling (N-acetylaspartate (NAA)), and inflammation (total creatine (tCr), total choline (tCho), myo-inositol (mI)) in the brain. OBJECTIVE: This study aims to investigate how ocrelizumab and interferon...

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Detalles Bibliográficos
Autores principales: MacMillan, Erin L, Schubert, Julia J, Vavasour, Irene M, Tam, Roger, Rauscher, Alexander, Taylor, Carolyn, White, Rick, Garren, Hideki, Clayton, David, Levesque, Victoria, Li, David KB, Kolind, Shannon H, Traboulsee, Anthony L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796216/
https://www.ncbi.nlm.nih.gov/pubmed/31662881
http://dx.doi.org/10.1177/2055217319879952