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CircPLEKHM3 acts as a tumor suppressor through regulation of the miR-9/BRCA1/DNAJB6/KLF4/AKT1 axis in ovarian cancer

BACKGROUND: Emerging evidence has shown that circular RNAs (circRNAs) play essential roles in cancer biology and are potential biomarkers and targets for cancer therapy. However, the expression and function of circRNAs in ovarian carcinogenesis and its progression remain elusive. METHODS: RNA sequen...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Zhou, Qing, Qiu, Qiongzi, Hou, Ling, Wu, Mengting, Li, Jia, Li, Xufan, Lu, Bingjian, Cheng, Xiaodong, Liu, Pengyuan, Lu, Weiguo, Lu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796346/
https://www.ncbi.nlm.nih.gov/pubmed/31623606
http://dx.doi.org/10.1186/s12943-019-1080-5