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Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity

BACKGROUND: Gold nanoparticles (Au-NPs) have extensive applications in electronics and biomedicine, resulting in increased exposure and prompting safety concerns for human health. After absorption, nanoparticles enter circulation and effect endothelial cells. We previously showed that exposure to Au...

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Detalles Bibliográficos
Autores principales: Chen, Ching-Yi, Liao, Po-Lin, Tsai, Chi-Hao, Chan, Yen-Ju, Cheng, Yu-Wen, Hwang, Ling-Ling, Lin, Kuan-Hung, Yen, Ting-Ling, Li, Ching-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796418/
https://www.ncbi.nlm.nih.gov/pubmed/31619255
http://dx.doi.org/10.1186/s12989-019-0324-2