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Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity
BACKGROUND: Gold nanoparticles (Au-NPs) have extensive applications in electronics and biomedicine, resulting in increased exposure and prompting safety concerns for human health. After absorption, nanoparticles enter circulation and effect endothelial cells. We previously showed that exposure to Au...
Autores principales: | Chen, Ching-Yi, Liao, Po-Lin, Tsai, Chi-Hao, Chan, Yen-Ju, Cheng, Yu-Wen, Hwang, Ling-Ling, Lin, Kuan-Hung, Yen, Ting-Ling, Li, Ching-Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796418/ https://www.ncbi.nlm.nih.gov/pubmed/31619255 http://dx.doi.org/10.1186/s12989-019-0324-2 |
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