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Tumor-infiltrating B cells affect the progression of oropharyngeal squamous cell carcinoma via cell-to-cell interactions with CD8(+) T cells

BACKGROUND: Standard treatment of oropharyngeal squamous cell carcinoma (OPSCC) is associated with high morbidity, whereas immunotherapeutic approaches using PD-1:PD-L1 checkpoint blockade only show moderate response rates in OPSCC patients. Therefore, a better stratification of patients and the dev...

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Detalles Bibliográficos
Autores principales: Hladíková, Kamila, Koucký, Vladimír, Bouček, Jan, Laco, Jan, Grega, Marek, Hodek, Miroslav, Zábrodský, Michal, Vošmik, Milan, Rozkošová, Kateřina, Vošmiková, Hana, Čelakovský, Petr, Chrobok, Viktor, Ryška, Aleš, Špíšek, Radek, Fialová, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796441/
https://www.ncbi.nlm.nih.gov/pubmed/31623665
http://dx.doi.org/10.1186/s40425-019-0726-6