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Prospective qualification of early cerebral biomarkers in a randomised trial of treatment with xenon combined with moderate hypothermia after birth asphyxia

BACKGROUND: The TOBY-Xe proof of concept randomised trial found no effect of xenon combined with hypothermia after birth asphyxia on the lactate to N-acetyl aspartate ratio (Lac/NAA) in the thalamus and fractional anisotropy (FA) in white matter tracts measured within 15 days of birth. To confirm th...

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Detalles Bibliográficos
Autores principales: Azzopardi, Denis, Chew, Andrew T., Deierl, Aniko, Huertas, Angela, Robertson, Nicola J., Tusor, Nora, Edwards, A. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796501/
https://www.ncbi.nlm.nih.gov/pubmed/31451436
http://dx.doi.org/10.1016/j.ebiom.2019.08.034