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NMDA receptor modulation of glutamate release in activated neutrophils

BACKGROUND: Neutrophil depletion improves neurologic outcomes in experimental sepsis/brain injury. We hypothesized that neutrophils may exacerbate neuronal injury through the release of neurotoxic quantities of the neurotransmitter glutamate. METHODS: Real-time glutamate release by primary human neu...

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Detalles Bibliográficos
Autores principales: del Arroyo, Ana Gutierrez, Hadjihambi, Anna, Sanchez, Jenifer, Turovsky, Egor, Kasymov, Vitaly, Cain, David, Nightingale, Tom D., Lambden, Simon, Grant, Seth G.N., Gourine, Alexander V., Ackland, Gareth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796524/
https://www.ncbi.nlm.nih.gov/pubmed/31401196
http://dx.doi.org/10.1016/j.ebiom.2019.08.004