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Obese mice exposed to psychosocial stress display cardiac and hippocampal dysfunction associated with local brain-derived neurotrophic factor depletion

INTRODUCTION: Obesity and psychosocial stress (PS) co-exist in individuals of Western society. Nevertheless, how PS impacts cardiac and hippocampal phenotype in obese subjects is still unknown. Nor is it clear whether changes in local brain-derived neurotrophic factor (BDNF) account, at least in par...

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Detalles Bibliográficos
Autores principales: Agrimi, Jacopo, Spalletti, Cristina, Baroni, Carlotta, Keceli, Gizem, Zhu, Guangshuo, Caragnano, Angela, Matteucci, Marco, Chelko, Stephen, Ramirez-Correa, Genaro A., Bedja, Djahida, Casieri, Valentina, Di Lascio, Nicole, Scalco, Arianna, Beltrami, Antonio Paolo, Paolocci, Nazareno, Caleo, Matteo, Lionetti, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796537/
https://www.ncbi.nlm.nih.gov/pubmed/31492565
http://dx.doi.org/10.1016/j.ebiom.2019.08.042