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Blockade of the kallikrein-kinin system reduces endothelial complement activation in vascular inflammation

BACKGROUND: The complement and kallikrein-kinin systems (KKS) are activated during vascular inflammation. The aim of this study was to investigate if blockade of the KKS can affect complement activation on the endothelium during inflammation. METHODS: Complement deposition on endothelial microvesicl...

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Detalles Bibliográficos
Autores principales: Lopatko Fagerström, Ingrid, Ståhl, Anne-lie, Mossberg, Maria, Tati, Ramesh, Kristoffersson, Ann-Charlotte, Kahn, Robin, Bascands, Jean-Loup, Klein, Julie, Schanstra, Joost P., Segelmark, Mårten, Karpman, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796560/
https://www.ncbi.nlm.nih.gov/pubmed/31444145
http://dx.doi.org/10.1016/j.ebiom.2019.08.020