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Intradermal vaccination prevents anti-MOG autoimmune encephalomyelitis in macaques
BACKGROUND: Autoimmune demyelinating diseases (ADD) are a major cause of neurological disability due to autoreactive cellular and humoral immune responses against brain antigens. A cure for chronic ADD could be obtained by appropriate immunomodulation. METHODS: We implemented a preclinical scheme to...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796575/ https://www.ncbi.nlm.nih.gov/pubmed/31492559 http://dx.doi.org/10.1016/j.ebiom.2019.08.052 |