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TCR repertoire and CDR3 motif analyses depict the role of αβ T cells in Ankylosing spondylitis
BACKGROUND: Ankylosing spondylitis (AS) is a chronic inflammatory disease with worldwide high prevalence. Although AS is strongly associated with HLA-B27 MHC-I antigen presentation, the role played by αβ T cells in AS remains elusive. METHODS: Utilizing TCRβ repertoire sequencing and bioinformatics...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796593/ https://www.ncbi.nlm.nih.gov/pubmed/31477563 http://dx.doi.org/10.1016/j.ebiom.2019.07.032 |