Targeted Delivery of C/EBPα-saRNA by RNA Aptamers Shows Anti-tumor Effects in a Mouse Model of Advanced PDAC

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies; it preferentially metastasizes to the liver and is the main cause of death from this disease. In previous studies, small activating RNA against CCAAT/enhancer-binding protein-α (C/EBPα-saRNA) demonstrated efficacy of...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoon, Sorah, Huang, Kai-Wen, Andrikakou, Pinelopi, Vasconcelos, Daniel, Swiderski, Piotr, Reebye, Vikash, Sodergren, Mikael, Habib, Nagy, Rossi, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796740/
https://www.ncbi.nlm.nih.gov/pubmed/31546149
http://dx.doi.org/10.1016/j.omtn.2019.08.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796740/
https://www.ncbi.nlm.nih.gov/pubmed/31546149
http://dx.doi.org/10.1016/j.omtn.2019.08.017

Ejemplares similares