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A Novel Peptide Nucleic Acid against the Cytidine Monophosphate Kinase of S. aureus Inhibits Staphylococcal Infection In Vivo

Here, we report a novel bactericidal peptide nucleic acid (PNA) that can induce the antisense effect on the cytidine monophosphate kinase (Cmk) of Staphylococcus aureus, a putative essential component for bacterial species. Based on the genome sequence of S. aureus N315, a set of PNA conjugates with...

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Detalles Bibliográficos
Autores principales: Lee, Hyung Tae, Kim, Se Kye, Lee, Jun Bong, Yoon, Jang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796767/
https://www.ncbi.nlm.nih.gov/pubmed/31581048
http://dx.doi.org/10.1016/j.omtn.2019.08.021