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Molecular basis for hierarchical histone de-β-hydroxybutyrylation by SIRT3
Chemical modifications on histones constitute a key mechanism for gene regulation in chromatin context. Recently, histone lysine β-hydroxybutyrylation (Kbhb) was identified as a new form of histone acylation that connects starvation-responsive metabolism to epigenetic regulation. Sirtuins are a fami...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796883/ https://www.ncbi.nlm.nih.gov/pubmed/31636949 http://dx.doi.org/10.1038/s41421-019-0103-0 |