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Molecular Cobalt(II) Complexes for Tau Polymerization in Alzheimer’s Disease

[Image: see text] Tau is an axonal protein known to form abnormal aggregates and is the biomarker of Alzheimer’s disease. Metal-based therapeutics for inhibition of Tau aggregation is limited and rarely reported in contemporary science. Here, we report the first example of rationally designed molecu...

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Detalles Bibliográficos
Autores principales: Gorantla, Nalini Vijay, Landge, Vinod G., Nagaraju, Pramod Gudigenahally, Priyadarshini CG, Poornima, Balaraman, Ekambaram, Chinnathambi, Subashchandrabose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796896/
https://www.ncbi.nlm.nih.gov/pubmed/31646215
http://dx.doi.org/10.1021/acsomega.9b00692