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NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly

The impairment of mitochondrial bioenergetics, often coupled with exaggerated reactive oxygen species (ROS) production, is a fundamental disease mechanism in organs with a high demand for energy, including the heart. Building a more robust and safer cellular powerhouse holds the promise for protecti...

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Detalles Bibliográficos
Autores principales: Hou, Tingting, Zhang, Rufeng, Jian, Chongshu, Ding, Wanqiu, Wang, Yanru, Ling, Shukuan, Ma, Qi, Hu, Xinli, Cheng, Heping, Wang, Xianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796901/
https://www.ncbi.nlm.nih.gov/pubmed/31366990
http://dx.doi.org/10.1038/s41422-019-0208-x