Cargando…
NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly
The impairment of mitochondrial bioenergetics, often coupled with exaggerated reactive oxygen species (ROS) production, is a fundamental disease mechanism in organs with a high demand for energy, including the heart. Building a more robust and safer cellular powerhouse holds the promise for protecti...
Autores principales: | Hou, Tingting, Zhang, Rufeng, Jian, Chongshu, Ding, Wanqiu, Wang, Yanru, Ling, Shukuan, Ma, Qi, Hu, Xinli, Cheng, Heping, Wang, Xianhua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796901/ https://www.ncbi.nlm.nih.gov/pubmed/31366990 http://dx.doi.org/10.1038/s41422-019-0208-x |
Ejemplares similares
-
NDUFAB1 protects against obesity and insulin resistance by enhancing mitochondrial metabolism
por: Zhang, Rufeng, et al.
Publicado: (2019) -
Structure and Mechanism of Respiratory III–IV
Supercomplexes in Bioenergetic Membranes
por: Brzezinski, Peter, et al.
Publicado: (2021) -
Mitochondrial flashes regulate ATP homeostasis in the heart
por: Wang, Xianhua, et al.
Publicado: (2017) -
Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability
por: Bohovych, Iryna, et al.
Publicado: (2015) -
Mitochondrial supercomplex assembly regulates metabolic features and glutamine dependency in mammalian cells
por: Zhang, Kun, et al.
Publicado: (2023)