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Regulation of zebrafish dorsoventral patterning by phase separation of RNA-binding protein Rbm14

RNA-binding proteins with intrinsically disordered regions (IDRs) such as Rbm14 can phase separate in vitro. To what extent the phase separation contributes to their physiological functions is however unclear. Here we show that zebrafish Rbm14 regulates embryonic dorsoventral patterning through phas...

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Detalles Bibliográficos
Autores principales: Xiao, Yue, Chen, Jiehui, Wan, Yihan, Gao, Qi, Jing, Naihe, Zheng, Yixian, Zhu, Xueliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796953/
https://www.ncbi.nlm.nih.gov/pubmed/31636951
http://dx.doi.org/10.1038/s41421-019-0106-x