PacBio Amplicon Sequencing Method To Measure Pilin Antigenic Variation Frequencies of Neisseria gonorrhoeae

Gene diversification is a common mechanism pathogens use to alter surface structures to aid in immune avoidance. Neisseria gonorrhoeae uses a gene conversion-based diversification system to alter the primary sequence of the gene encoding the major subunit of the pilus, pilE. Antigenic variation occu...

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Detalles Bibliográficos
Autores principales: Ozer, Egon A., Prister, Lauren L., Yin, Shaohui, Ward, Billy H., Ivanov, Stanimir, Seifert, H Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796969/
https://www.ncbi.nlm.nih.gov/pubmed/31578246
http://dx.doi.org/10.1128/mSphere.00562-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796969/
https://www.ncbi.nlm.nih.gov/pubmed/31578246
http://dx.doi.org/10.1128/mSphere.00562-19

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