Polymorphisms in vasoactive eicosanoid genes of kidney donors affect biopsy scores and clinical outcomes in renal transplantation

Cytochrome P450 (CYP) enzymes metabolize arachidonic acid to vasoactive eicosanoids such as epoxyeicosatrienoic acids (EETs) and 20-Hydroxyeicosatetraenoic acid (20-HETE), whilst soluble epoxide hydrolase, encoded by the EPHX2 gene, is in charge of EETs degradation. We aimed to analyze the influence...

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Detalles Bibliográficos
Autores principales: Mota-Zamorano, Sonia, González, Luz M., Luna, Enrique, Fernández, José J., Gómez, Áurea, Nieto-Fernández, Alberto, Robles, Nicolás R., Gervasini, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797116/
https://www.ncbi.nlm.nih.gov/pubmed/31622444
http://dx.doi.org/10.1371/journal.pone.0224129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797116/
https://www.ncbi.nlm.nih.gov/pubmed/31622444
http://dx.doi.org/10.1371/journal.pone.0224129

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