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A hormone receptor pathway cell-autonomously delays neuron morphological aging by suppressing endocytosis
Neurons have a lifespan that parallels that of the organism and are largely irreplaceable. Their unusually long lifespan predisposes neurons to neurodegenerative disease. We sought to identify physiological mechanisms that delay neuron aging in Caenorhabditis elegans by asking how neuron morphologic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797217/ https://www.ncbi.nlm.nih.gov/pubmed/31589601 http://dx.doi.org/10.1371/journal.pbio.3000452 |