Low affinity binding sites in an activating CRM mediate negative autoregulation of the Drosophila Hox gene Ultrabithorax

Specification of cell identity and the proper functioning of a mature cell depend on precise regulation of gene expression. Both binary ON/OFF regulation of transcription, as well as more fine-tuned control of transcription levels in the ON state, are required to define cell types. The Drosophila me...

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Detalles Bibliográficos
Autores principales: Delker, Rebecca K., Ranade, Vikram, Loker, Ryan, Voutev, Roumen, Mann, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797233/
https://www.ncbi.nlm.nih.gov/pubmed/31589607
http://dx.doi.org/10.1371/journal.pgen.1008444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797233/
https://www.ncbi.nlm.nih.gov/pubmed/31589607
http://dx.doi.org/10.1371/journal.pgen.1008444

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