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2120: Antipsychotic-induced weight gain arises, in part, from alteration of feeding circuitry in the lateral hypothalamic area

OBJECTIVES/SPECIFIC AIMS: To demonstrate that olanzapine recapitulates the effect of increased lateral hypothalamic (LH) GABAergic activity in the DRN and the DBB. This will provide a potential neural substrate for the observed increase in consumption of food and weight gain. METHODS/STUDY POPULATIO...

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Detalles Bibliográficos
Autores principales: Michael Cassidy, Ryan, Savage, Hannah, Lu, Yungang, Yang Zhang, Xiang, Tong, Qingchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797376/
http://dx.doi.org/10.1017/cts.2017.22