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ASPEN, a methodology for reconstructing protein evolution with improved accuracy using ensemble models

Evolutionary reconstruction algorithms produce models of the evolutionary history of proteins or species. Such algorithms are highly sensitive to their inputs: the sequences used and their alignments. Here, we asked whether the variance introduced by selecting different input sequences could be used...

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Detalles Bibliográficos
Autores principales: Sloutsky, Roman, Naegle, Kristen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797483/
https://www.ncbi.nlm.nih.gov/pubmed/31621582
http://dx.doi.org/10.7554/eLife.47676