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Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient

The process by which fibroblasts are directly reprogrammed into cardiomyocytes involves two stages; initiation and maturation. Initiation represents the initial expression of factors that induce fibroblasts to transdifferentiate into cardiomyocytes. Following initiation, the cell undergoes a period...

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Detalles Bibliográficos
Autores principales: Dal-Pra, Sophie, Hodgkinson, Conrad P., Dzau, Victor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797484/
https://www.ncbi.nlm.nih.gov/pubmed/31622977
http://dx.doi.org/10.1371/journal.pone.0223842