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Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient
The process by which fibroblasts are directly reprogrammed into cardiomyocytes involves two stages; initiation and maturation. Initiation represents the initial expression of factors that induce fibroblasts to transdifferentiate into cardiomyocytes. Following initiation, the cell undergoes a period...
Autores principales: | Dal-Pra, Sophie, Hodgkinson, Conrad P., Dzau, Victor J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797484/ https://www.ncbi.nlm.nih.gov/pubmed/31622977 http://dx.doi.org/10.1371/journal.pone.0223842 |
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